This presentation introduces the sweetpotato whitefly, Bemisia tabaci, as an important pest in the production of cucurbits. It focuses on whitefly diversity, the direct effects of the whitefly on squash, and the indirect effects of the whitefly as a vector of criniviruses and begomoviruses infecting squash. The presentation also addresses modes of virus transmission and pathosystem component interactions among the whitefly, squash, and squash-infecting viruses. Finally, the presentation focuses on management of the whitefly and whitefly-transmitted viruses in the southeastern United States.