This presentation will help consultants, growers, and other practitioners understand the fundamentals of early generation seed potato production, from tissue culture to minituber production. Early generation potato production relies on the development of disease-free tissue culture plantlet banks and the careful production of minitubers, which includes close monitoring of the crop for pests, diseases, and variety mixtures. By the end of the presentation, viewers should understand the process of producing a large crop of potato tubers from a single disease-tested tissue culture plantlet and should be able to use this knowledge to help evaluate the health of a seed potato crop.