This presentation will help growers, seed certification and regulatory officials, consultants, and other practitioners in the United States understand how and why Potato virus Y (PVY) is affecting the seed potato crop and why, if left unchecked, it will become a major disease issue for the food sector of the potato industry. Specifically, the presentation addresses the reemergence of PVY as a disease problem in seed potatoes; how regulatory, business, and science-based activities have addressed the problem; and what steps can be and are being taken to manage the disease and prevent the newly introduced tuber necrotic strains of the virus from becoming a major quality issue for potato growers. By the end of this presentation, practitioners should understand the emerging PVY problem and know more about the existing and developing strategies that seed certification programs and growers, especially seed growers, can use to control PVY.